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Returning to work the following Monday, 19 April, Hofmann made a decision to intentionally check the LSD-25 on himself to root out the weirdness with the prior week. Realizing the prospective toxicity of ergot-linked compounds, he showed good caution in restricting his First dose to 250 micrograms (μg) – 750 μg shy of one milligram (mg). Hofm